The Chronicles of Sheldon Mayer's Sugar & Spike
Better Late Than Never!
Sugar & Spike #54 
Ah, poor old "No-Feets", long suffering pet fish who manages to narrowly avoid catastrophe at the hands of Sugar and Spike time and time again. You'd think parents with such active kids around would think twice about having a fish in a glass bowl precariously balanced on top of a pole.
I guess he belongs to the Plumms, based on this story, but I'm not sure if that's consistent. I think he shows up wherever it's most convenient for the joke of the moment.
Anyway, a nice little story in just six panels. I especially liked the attention paid to the face of No-Feets, going from suspicious to resigned to scowling.
Characters: Sugar, Spike, No-Feets, Mrs. Plumm (hands only)
Property Damage: No-Feets came out unscathed, but that toothpaste tube is a goner
"I must say, your mother is broadminded! Mine frowns on this sort of thing!"