The Chronicles of Sheldon Mayer's Sugar & Spike
Little Arthur Becomes a Mad Professor!
Sugar & Spike #42 
Dedication: Carol Chernoff (age 12), Illinois
One of the major recurring characters in the series is Little Arthur, a slightly older boy whose mother Myrna often brings him over. Arthur first appears in #17, returns in #22 and then shows up every few issues for the rest of the series, including the new material drawn in the 1980s. Arthur is quite a terror, so the kids learn to dread his visits, which usually consist of Arthur pulling Sugar's ponytail, which leads to Spike biting him. Arthur is old enough that he speaks grown-up talk rather than baby-talk, so he lie about what happened, getting the kids punished (as Sugar once says, he doesn't so much speak in grown-up talk as he fibs in it). Of course, his plans always backfire (I don't think the Comics Code allowed them to show success through lying).
In this variation, Arthur has a new interest in medicine, and pretty much ignores Sugar and Spike as he works on his plans for a self-propelled stretcher. The kids figure he must be sick, and are quite happy with that, until Arthur tries to put his ideas into practice, converting a coffee table to a stretcher and trying to use them as test patients.
Characters: Sugar, Spike, Mrs. Wilson, Mrs. Plumm, Little Arthur, Myrna
Damage: That coffee table is history, all Arthur's fault. The lamp, that was all Spike
"He should be sick more often! It improves him!"